In Week 15 against the Tennessee Titans, the 49ers surrendered 14 points in the fourth quarter. In Week 11 against the Arizona Cardinals, they allowed 12 points in the final quarter. Against the New York Giants, San Francisco again gave up 14 fourth-quarter points but responded by scoring the same amount to secure the win.

The NFL season continues in Week 15 when the San Francisco 49ers host the Tennessee Titans on Sunday. Start time, how to watch, stream and NFL TV schedule.

San Francisco could suddenly be a dark-horse team to win the NFC West and get the conference's No. 1 overall seed.

The San Francisco 49ers got what they needed with the Seattle Seahawks win in Week 16, but one of their players learned a key lesson on a wacky play.

SANTA CLARA – Here is how the 49ers (10-4) graded in Sunday’s 37-24 home win over the Tennessee Titans (2-11):

Broadcast and streaming information for the San Francisco 49ers Week 16 'Monday Night Football' matchup against the Indianapolis Colts at Lucas Oil Stadium.

The San Francisco 49ers defense has been playing above its head all season. They have lost pieces, and while they have struggled at times, they have been good enough to hold a 10-4 record with just three games to play. Robert Saleh did not quite give away the secret formula, but he did let fans know one thing that is helping his defense.

Kickoff is at 8:15 p.m. ET from Lucas Oil Stadium in Indianapolis. The latest 49ers vs. Colts odds from DraftKings Sportsbook have San Francisco as 5.5-point road favorites, while the over/under for total points scored is 46. Before making any Colts vs. 49ers picks, be sure to see the NFL predictions from SportsLine's projection model.