The formation of amyloid fibrils and the aggregation of misfolded proteins are central to the pathology of Alzheimer’s disease. At the molecular level, normal proteins adopt aberrant conformations ...

Scientists from St Petersburg University and the University of Montpellier have developed the first software enabling the prediction of pairs of proteins in amyloid fibrils capable of co-aggregation, ...

After studying 140,000 versions of the Aβ42 peptide, scientists identified some of the earliest molecular interactions that drive the formation of harmful amyloid protein aggregates found in Alzheimer ...

It has long been known that a hallmark of Alzheimer's disease, and most other neurodegenerative diseases, is the clumping together of insoluble protein aggregates in the brain. During normal ...

Durable analytical instruments expedite the study of misfolded proteins linked to neurodegenerative diseases. To overcome these limitations, scientists developed the real-time quaking-induced ...

Illustration showing Alzheimer's disease affecting the hippocampus. Alzheimer's is a neurodegenerative disease that causes the loss of brain tissue. This leads to the progressive and irreversible loss ...

Mohali, have identified a new pathway involving nanoparticles to treat Alzheimers Disease (AD), said the Ministry of Science & Technology on Tuesday.

A designer version of the tau protein, developed by a team led by UT Southwestern Medical Center researchers, maintains its ...

In a recent review published in the Journal of Neurochemistry, researchers evaluate the impact of the coronavirus disease 2019 (COVID-19) on Alzheimer's disease (AD) pathology. Study: COVID-19 and the ...