P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...

Researchers have uncovered a previously unrecognized role for immune cell surface sugars in driving inflammation in psoriasis. Scientists have refined how they understand the role of sugars called ...

Researchers have shown that the protein MCL1 not only inhibits programmed cell death, but also plays a central role in tumor ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...

A hidden “jack-in-the-box” mechanism inside T cells may hold the key to unlocking more powerful cancer immunotherapies.

The Warburg effect describes how cancer cells switch from oxidative phosphorylation to glycolysis even in oxygen-rich ...

No one has yet created a fully functioning artificial cell. But a research team at Aarhus University has taken a step in that direction: ...

Plants form a critical model for understanding regulated cell death (RCD) as part of their sophisticated immune responses. In the ongoing evolutionary arms ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...