Proteomic analyses of neurodegenerative diseases revealed massive variations, both as an increase or decrease, in the amount of a plethora of cellular proteins. These variations may be meaningful per ...
It has long been known that a hallmark of Alzheimer's disease, and most other neurodegenerative diseases, is the clumping together of insoluble protein aggregates in the brain. During normal ...
Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was ...
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Mitochondrial protein that 'erases' Huntington’s aggregates
DGIST has made a groundbreaking announcement: a research team, under the guidance of professors Jiwon Um and Jaewon Ko, has achieved a global first by elucidating the function of ‘ClpB.’ ...
Unlike our organs, cell organelles such as mitochondria are not fixed in place, but when, where, how, and why organelles move remain unclear. Research published in the Biophysical Journal shows that ...
The new treatment leverages peptide-brush polymers, which act as a shield to prevent proteins from binding to one another. Polymer backbone is shown in yellow. Active peptides are in blue and green.
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