In the past decade, our understanding of the role of podocytes in the function of the glomerular filtration barrier, and of the role of podocyte injury in the pathogenesis of proteinuric kidney ...

IgA nephropathy (IgAN) is the most common type of primary glomerular nephritis in Southeast Asia. 1 It has an extremely variable clinical course, ranging from persistent asymptomatic microscopic ...

Podocytes are a terminally differentiated cell type located in the glomerulus. Podocyte damage and the subsequent dysregulation of podocyte proteins have been implicated in various kidney disorders.

A study published in Advanced Healthcare Materials describes the bioengineering of three-dimensional (3D) kidney glomerular microtissues that replicate the glomerular filtration barrier (GFB) ...

Podocyte-specific targeting of OTUD5 alleviates diabetic kidney disease July 10, 2024 ...

Professor and Consultant Paediatric Nephrologist, Bristol Children's Hospital; Director of Bristol Renal; Glomerular disease research including podocyte biology and nephrotic syndromes; Founder and ...

The Clinical Implications of Basic Research series has focused on highlighting laboratory research that could lead to advances in clinical therapeutics. However, the path between the laboratory and ...