While prokaryotic cells do not have membrane-bound structures, they do have distinct cellular regions (Figure 1). In prokaryotic cells, DNA bundles together in a region called the nucleoid. Primitive ...

Replication forks can stall because of an encounter with a DNA-template lesion. The template damage can be from either exogenous or endogenous sources. Stalled forks can lead to genomic instability.

The main difference between prokaryotic and eukaryotic cells lies in their structure. Prokaryotic cells and eukaryotic cells are the two types of cells that exist on Earth. There are several ...

In this article, we discuss the role that horizontal gene transfer might have had in shaping the complement of DNA-replication proteins in the bacterial, archaeal and eukaryotic core replication ...