Crystal structures of the Escherichia coli DNA replication γ clamp loading complex and of a subunit of the clamp loader bound to a β clamp monomer provide a physical framework in which to view ...
The Escherichia coli clamp loader, γ-complex, loads the ring-shaped β-clamp onto DNA in an ATP driven reaction in which the clamp is cracked open, brought to a primed site and closed around the DNA.
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