Netrin1 is a protein that was first characterized for its axon guidance activities during embryonic development. The netrin family has been shown to play many critical roles in developmental and ...

Researchers have uncovered a surprising new role for netrin1, a crucial protein in neural development, as a regulator that limits bone morphogenetic protein signaling in the developing spinal cord.

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have uncovered an unexpected role for the molecule netrin1 in organizing the developing spinal ...

Spinal cord injury (SCI) causes structural damage to neural circuits, which in turn leads to sensory and motor dysfunction. Transplantation of neural precursor cells/stem cells provides a potential ...

Boosting communication between the spinal nerves and the muscles using the spinal cord stimulation reverses spinal muscle atrophy (SMA) progression and could be applied to other motoneuron diseases, ...

A new drug-free, minimally invasive intervention targets the root cause of progressive loss of neural function in spinal ...

When a vertebrate embryo develops, a group of cells self-organizes into the neural tube, eventually becoming the brain and the spinal cord. This involves specific signals, but how these signals are ...

Researchers at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences explored the regenerative mechanisms behind spinal cord injury (SCI) repair. By constructing ...

A phase 1 clinical trial demonstrated the long-term safety and feasibility of neural stem cell transplantation for treating chronic spinal cord injuries. The corresponding study was published in Cell ...

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have uncovered an unexpected role for the molecule netrin1 in organizing the developing spinal ...