A new study currently available on the Research Square* preprint server has pointed out that molnupiravir treatment increases the ratio of transition to transversion mutations in coronavirus disease ...
AID-induced U/G lesions can be perfectly repaired or may result in C/G transition mutations via DNA replication, C/G transition or transversion mutations via the BER pathway, and A/T mutations via the ...
Activation-induced deaminase (AID) initiates hypermutation of Ig genes in activated B cells by converting C:G into U:G base pairs. G₁-phase variants of uracil base excision repair (BER) and mismatch ...