The synthesis and subsequent functionalisation of amides have emerged as pivotal areas in modern synthetic chemistry, enabling the direct conversion of these otherwise inert functional groups into ...

A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...

Amides are among the most ubiquitous functional groups in organic chemistry, forming the backbone of peptides and playing a vital role in pharmaceutical, synthetic and materials chemistry. Their ...

Takeaway 3: The Alcohol-to-Amide Shortcut The team extended their logic to create a "one-pot" enzymatic cascade that starts from broadly available aliphatic alcohols. This chemoenzymatic strategy is ...

A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid without ...

Chemists from HSE University and the Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences (INEOS RAS) have developed a new method for synthesising amides, essential ...

Amide Technologies has raised $16.5 million in venture capital to help commercialize its peptide production process. The process was developed from 2011 to 2017 in the lab of the Massachusetts ...

Extending or trimming the length of a drug molecule’s carbon backbone by just a couple of atoms can significantly alter its activity, even if nothing else in the structure changes. So reactions that ...