A compact Cas12f nuclease shows high editing efficiency in human cells, with structural insights enabling an engineered variant potentially suited for future AAV‑compatible delivery.

The US Food and Drug Administration (FDA) today issued a draft guidance for sponsors seeking approval of human gene therapy ...

The US Food and Drug Administration (FDA) has released draft guidance on how sponsors can utilize next-generation sequencing ...

The CRISPR-Cas gene-editing system has long been the focus of research as a promising tool in genome editing. However, the ...

The draft guidance supports the agency’s new pathway designed to speed up the development of custom gene therapies.

NIH-funded UT team and colleagues from Metagenomi Thereapeutics discovered highly efficient enzyme could enable targeted gene editing within the human body.

TOKYO: The government is set to prohibit the creation of genome-edited babies by modifying the genetic information of embryos ...

The rapid evolution of CRISPR/Cas genome editing has redefined the possibilities of cellular and gene therapy, enabling precise correction ...

So far, clinical applications of CRISPR-based gene editing have been largely limited to editing a person's cells outside of their body and then ...

CRISPR Cas9 gene therapy explained with DNA scissors, hereditary diseases treatment, and designer babies ethical dilemmas ...

The rapid evolution of CRISPR/Cas genome editing has redefined the possibilities of cellular and gene therapy, enabling precise correction, ...

The genome has thousands of genes that code for proteins, which help carry out many of the cell's important functions. But ...