University of Utah researchers at the Pulst-Scoles Laboratory have discovered that reducing levels of the STAUFEN-1 protein ...

When it comes to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and certain forms of dementia, ...

Prefoldin 5 stabilises neuronal microtubules and suppresses Tau-mediated neurotoxicity, offering a potential therapeutic target for tauopathies.

The FDA granted fast track status to VectorY’s VTx-002, an antibody gene therapy targeting TDP-43 protein aggregates in ALS.

Richard Silverman, PhD, is a Northwestern University chemist whose name bears the building. His experimentation led to the ...

DGIST has made a groundbreaking announcement: a research team, under the guidance of professors Jiwon Um and Jaewon Ko, has achieved a global first by elucidating the function of ‘ClpB.’ ...

A designer version of the tau protein, developed by a team led by UT Southwestern Medical Center researchers, maintains its biological function while resisting aggregation, a pathological trait linked ...

ANN ARBOR—Inside the cell reside many tiny assembly factories and warehouses that gather together all of the proteins and RNAs—which carry out instructions from our DNA—that a living being needs.

Please provide your email address to receive an email when new articles are posted on . In this Healio video, David G. Standaert, MD, PhD, discusses a plenary session on protein aggregate clearance in ...

How long can someone bail water before the boat tips over? That depends on two opposing factors: the rush of water, and the fitness of the bailer. A similar push-and-pull may take place in ...

On a quiet farm in Erie County, Pennsylvania, 67-year-old Diane Zaczyk used to think nothing of hefting 50-pound sacks of chicken feed onto her shoulder. Strong, stubborn and devoted to caring for her ...